What is the Most Effective Weight Loss Pill?

Long-Term Prescription Weight-Loss Pills

The most effective weight loss pill for you is one that helps you lose 5-10% of your initial body weight with few or tolerable side effects. Prescription weight-loss drugs that you can use for more than 12 weeks lead to major weight loss compared to an inactive treatment.

Medications in Clinical Trials

• Oral semaglutide
• Orforglipron
• Amycretin

Dietary Supplements

Dietary supplements often have vitamins, minerals, fiber, caffeine, herbs, and other plants. Some of the most popular supplements claim to improve diet, boost metabolism, and suppress appetite.